In the early stages of human embryogenesis, a transcription factor called Twist1 plays a key regulatory role in how the embryo assumes form and function. Much later in life, however, researchers at the University of California, San Diego School of Medicine, say Twist1 can re-emerge, taking a darker and more deadly turn.
Cancer Cell
—University of California, San Diego Health Sciences
New research may be relevant to how a mother’s diet during pregnancy influences obesity in her children. Rats fed a high-fat prenatal diet had offspring that were obese, an effect prevented by prenatal antixodidants.
—Children's Hospital of Philadelphia
Researchers discovered a new, key component in the spread of lung cancer as well as a likely way to block it with drugs now in clinical trial. The study was published today (Monday, March 14) in the Journal of Clinical Investigation.
Journal of Clinical Investigation
—University of Texas M. D. Anderson Cancer Center
St. Jude Children’s Research Hospital investigators use a novel model system to show how specific mutations can induce glioma formation in multiple regions of the brain and to begin studying patient response to a new generation of targeted therapies.
Cancer Cell
—St. Jude Children's Research Hospital
New research from the Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) shows that newer, more expensive treatment options for prostate cancer were adopted rapidly and widely during 2002 – 2005 without proof of their cost-effectiveness.
A meta-analysis of nine previous studies found that quitting smoking shortly before surgery was not associated with an increased risk of postoperative complications, according to a report published online today that will appear in the July 11 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
